Our group develops new platform technologies for cell and gene therapy. To this end, we converge knowledge and techniques of cell/gene/tissue engineering, drug delivery, biomaterials, micro/macro-fluidic bioreactors, transport phenomena, chemical
My laboratory is studying the molecular basis of pathogenesis of bacterial species, Borrelia burgdorferi, Treponema pallidum and Pseudomonas aeruginosa. These clinically important bacterial pathogens are transmitted to humans using different
The research in my laboratory is focused on understanding the functions and mechanisms of enzymes involved in genome replication and transcription. We use among various methods transient state kinetics (rapid
Epithelial ovarian cancer (EOC) remains the most lethal gynecological malignancy in the United States. Implementing immunotherapeutic approaches to treat this disease holds promise, as the ovarian cancer microenvironment is immunologically
Research in the Pilch lab is focused on the identification of novel antibacterial targets and the development of new antibiotics that can be used in the treatment of infections caused
My lab is exploring the human antibody responses towards the two pathogens responsible for the most devastating diseases around the world, HIV-1 and TB. Our focus in the HIV field
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Our research studies three stages of the retroviral life-cycle: entry, replication and integration. Retroviruses are RNA viruses capable of inducing various diseases including cancers and immunodeficiencies. The focus of our
Dr. Salje’s research focuses on understanding how obligate intracellular bacteria interact with their eukaryotic host cells and how this causes disease. Research is primarily focused on rickettsial organisms, a family
The Sant’Angelo lab works on transcription factors that define T cell effector functions. In particular, the lab has focused on the genes that induce a subset of T cells, natural